Leigh Lab

Regenerative immunology

Publications

Here you will find our publications and accompanying resources. For a full list of Nick’s work check out Google Scholar

Publications:


Brown T*, Mishra K*, Elewa A*, Iarovenko S*, Subramanian E, Joven Araus A, Petzold A, Fromm B, Friedländer MR, Rikk L, Suzuki M, Suzuki KT, Hayashi T, Toyoda A, Oliveira CR, Osipova E, Leigh ND✉️ ,Yun MH✉️, Simon A✉️. Chromosome-scale genome assembly reveals how repeat elements shape non-coding RNA landscapes active during newt limb regeneration. Cell Genomics. 27 January 2025.✉️ co-corresponding/last author, * co-first author

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Cardiello JF, Araus AJ, Giatrellis S, Simon A, Leigh ND. Evaluation of genetic demultiplexing of single-cell sequencing data from model species. Life Science Alliance. 17 May 2023.




Leigh ND, Currie JD. Rebuilding limbs, one cell at a time. Developmental Dynamics. 16 February 2022.





Stegmayr J, Alsafadi HN, Langwinski W, Niroomand A, Lindstedt S, Leigh ND, Wagner DE. Isolation of high yield and quality RNA from human precision-cut lung slices for RNA-sequencing and computational integration with larger patient cohorts. AJP Lung and Cellular and Molecular Physiology. 28 Oct 2020.


Leigh ND, Sessa S., Dragalzew AC, Payzin-Dogru D, Sousa JF, Aggouras AN, Johnson K, Dunlap GS, Haas BJ, Levin M, Schneider I, Whited JL. von Willebrand factor D and EGF domains is an evolutionarily conserved and required feature of blastemas capable of multitissue appendage regeneration. Evolution & Development. 2020; 1– 15.


Leigh ND, Dunlap GS, Johnson K, Mariano R, Oshiro R, Wong AY, Bryant DM, Miller BM, Ratner A, Chen A, Ye WW, Haas BJ, Whited JL. Transcriptomic landscape of the blastema niche in regenerating adult axolotl limbs at single-cell resolution. Nature Communications 2018 9; 5153.

Pre-prints:


Brown T*, Elewa A*, Iarovenko S*, Subramanian E*, Araus AJ, Petzold A, Suzuki M, Suzuki KT, Hayashi T, Toyoda A, Oliveira C, Osipova E, Leigh ND✉️ , Simon A✉️ , Yun MH✉️ . Sequencing and chromosome-scale assembly of the giant Pleurodeles waltl genome bioRxiv October 22, 2022.✉️ co-corresponding/last author, * co-first author


Cardiello JF, Araus AJ, Giatrellis S, Simon A, Leigh ND. Accurate genotype-based demultiplexing of single cell RNA sequencing samples from non-human animals. bioRxiv Septermber 23, 2022.


Stegmayr J, Alsafadi HN, Langwinski W, Niroomand A, Lindstedt S, Leigh ND, Wagner DE. Isolation of high yield and quality RNA from human precision-cut lung slices for RNA-sequencing and computational integration with larger patient cohorts. bioRxiv August 22, 2020.


Leigh ND, Sessa S., Dragalzew AC, Payzin-Dogru D, Sousa JF, Aggouras AN, Johnson K, Dunlap GS, Haas BJ, Levin M, Schneider I, Whited JL. von Willebrand factor D and EGF domains is an evolutionarily conserved and required feature of blastemas capable of multitissue appendage regeneration. bioRxiv November 15, 2019.